Preheat the oven to 350 degrees Fahrenheit. Spray your bread pan with cooking spray. Line the pan with parchment paper, to help with removal, then spray the parchment lightly with cooking spray.
Use a dough cutter or sharp knife to divide each biscuit into 4 equal pieces.
Stir together the granulated sugar, brown sugar and ground cinnamon in your large mixing bowl.
Sprinkle 1 tablespoon of the cinnamon sugar mixture into the bottom of the bread pan.
Add the biscuits to the remaining cinnamon sugar mixture and stir to coat all the pieces.
Add the blueberries and stir them in.
Transfer the blueberry biscuits to the bread pan.
In a small mixing bowl, mix the butter, orange juice and vanilla extract together.
Pour the orange butter mixture over the biscuits in the bread pan.
Bake for 30-35 minutes or until the top is golden brown and no longer looks wet.
Cool in the pan for 5 minutes before running a knife around the edges. Flip the loaf onto a serving tray and let it stand, upside-down, for 2 minutes to allow the topping to drip around the loaf.
Turn the loaves upright and cool for another 5-7 minutes before slicing or serving warm as a pull apart bread.